Medicinal Cannabis Advances in 2017 – A Review

This literature review was conducted using Google Scholar, which was used to find citations of academic papers that referenced “cannabis medicine”, “cannabis psychosis”, “cannabis schizophrenia” and “medicinal cannabis”.

The strands of research that interest us here include: research undermining cannabis prohibition, with reference to psychiatric concerns; research supporting use of cannabis medicine, with reference to psychiatric conditions; evidence for cannabis as a substitute for opioids; other evidence supporting the use of cannabis medicine.

Research undermining cannabis prohibition, with reference to psychiatric concerns

This paper in the Biological Psychiatry Journal was notable for containing the sentence “Meta-analyses suggest that individuals with schizophrenia who use cannabis show better cognitive functioning compared to those who are non-users.”

Another paper in the Schizophrenia Bulletin makes a point of distinguishing between the effects of CBD and the effects of THC, noting that “THC is responsible for the psychotogenic effects of cannabis.” This directly contradicts the received psychiatric wisdom that “cannabis” causes psychosis.

This paper even notes that “independent evidence that CBD has antipsychotic and anxiolytic properties in patients with mental health disorders has been accumulating.” Indeed, doctors in California have been advising people for at least 10 years now that high-CBD strains (such as Northern Lights) were better suited for calming and sleeping purposes than high-THC skunk.

Although this paper is not titled with a journal of publication, it is worthwhile for at least conceding that many of the negative symptoms of schizophrenia are ameliorated by cannabis use.

This paper in the Acta Psychopathologica argues against the prohibition of cannabis on the basis of the Precautionary Principle. According to this paper, almost everyone tempted to smoke cannabis already has, regardless of the law. Moreover, prohibition prevents very few cases of schizophrenia, even assuming a direct causal link. Therefore, the deterrent effect of prohibition is outweighed by the positive effects of making it legal.

Research supporting use of cannabis medicine, with reference to psychiatric conditions

This paper in the the Clinical Psychology Review performed a meta-analysis of recent discoveries about the relationship between medicinal cannabis use and positive mental health outcomes. Perhaps the foremost result of this analysis was “Cannabis has potential for the treatment of PTSD and substance use disorders.” Among cannabis users this is well-known to be one of the main reasons why people smoke it in the first place. It was also noted that “Cannabis use does not appear to increase risk of harm to self or others.”

What is striking about this paper is the absence of Drug War rhetoric. Cannabis use, instead of being described as cannabis abuse (as in the majority of prohibitionist papers), is here given the acronym CTP (cannabis for therapeutic purposes). In the past, a paper that referred to cannabis in this manner would not have been funded or published, so the appearance of the phrase suggests that attitudes are changing.

A comprehensive overview of recent advances in medicinal cannabis science can be found in the Handbook of Cannabis and Related Pathologies Chapters 90 and 91, ‘The Use of Medical Marijuana in the Treatment of Psychiatric Disorders’ and ‘Beneficial Effects of Cannabis and Related Compounds on Sleep’.

Unfortunately, much of the literature continues to make the fundamental error of confusing cannabis extracts and pharamceutical preparations with the actual cannabis plant itself (as seen here). The authors of these papers frequently draw the conclusion that cannabis is not helpful for treating certain conditions because some extract was found to not be helpful. Others (as seen here) fail to make any distinction between THC and CBD, lumping all 100+ cannabinoids under the rubric of “marijuana”.

This paper notes that anxiety is one of the top five reasons given by patients in North America for using medicinal cannabis. It doesn’t go into why, but it’s likely that the calming effects of CBD are involved, as they may also be in the case of schizophrenia. Other papers also support the notion that cannabis has use for treating certain mental conditions, such as social anxiety.

Evidence for cannabis as a substitute for opioids

One of the most promising directions of future medicinal cannabis research appears to be in the direction of using cannabis as a substitute for a variety of other medicines that might have worse side-effects or addictive potential.

One of the most astonishing pieces of research was a study of how usage of pain, anxiety and sleep medication decreased when medicinal cannabis was available. In a survey of New England dispensary members, “among respondents that regularly used opioids, over three-quarters (76.7%) indicated that they reduced their use since they started [medicinal cannabis]…” and “…Approximately two-thirds of patients decreased their use of anti-anxiety (71.8%), migraine (66.7%), and sleep (65.2%) medications following [medicinal cannabis]…”.

Another example can be found here. The linked study is a literature review of 2897 medicinal cannabis patients that found “Respondents overwhelmingly reported that cannabis provided relief on par with their other medications, but without the unwanted side effects.”

In particular there seems to be special promise for cannabis to help with the opioid addiction crisis. Several papers suggest promise for cannabis to help here, as well as act as a substitute for sleep medications.

Other evidence supporting the use of cannabis medicine

Soporific uses appear to be one of the most promising avenues for future research into the benefits of medicinal cannabis. This study found reason to support the idea that cannabis heavy in CBDs is better suited for sleep management than cannabis heavy in THCs.

This review in Clinical Psychopharmacology and Medicine suggested that there might be promise in using cannabis to treat Alzheimers’s, Huntington’s and Parkinson’s diseases, among other neurodegenerative conditions.

Other studies suggest that there is promise for cannabis medicine in alleviating suffering associated with multiple sclerosis.

This study suggested that the savings from prescriptions that don’t get filled in legal cannabis states (because legal medicinal cannabis acts as a substitute for the prescribed medicine) could run into the billions.

What many of these studies have in common is a mention of the need for more research into the potential for cannabis to alleviate suffering, and a lament for the fact that this research has been hamstrung by cannabis prohibition. It’s clear that awareness of the benefits of cannabis medicine is spreading rapidly among the medical community, and that there is much excitement about future applications.

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Vince McLeod is a former Membership Secretary of the Aotearoa Legalise Cannabis Party and author of the Cannabis Activist’s Handbook.

Could New Zealand Ever Imagine Banning Rugby?

When even men built like this don’t want their kids playing rugby because it’s too violent, you know the sport has a problem

For decades, Kiwis have got used to the idea that wintertime means rugby. Well, we better start getting used to the idea of wintertime meaning soccer, because soon we’re going to have a lot more awareness about the effects of repetitive head injury than we do now, and when we do, there are going to be a lot of shrieking violets trying to get the game they play in heaven banned.

Rugby is popular in New Zealand for two major reasons. The first is that it’s fun as all hell both to play and to watch, the second is that rugby has been an important part of the masonry that cemented white people and Maoris together into a functioning modern culture. For over a century, rugby fields have been the places where Kiwis learned to set aside their racial and class differences and unite of their own free will towards a common goal.

There has always been an undercurrent of concerned mothers, however, who didn’t let their kids play rugby out of fear of head or brain injury. It’s an entirely legitimate concern – rugby is a collision sport, after all, and it’s evident from watching ten minutes of an All Blacks match that not even the best tackling technique in the world is a guarantee that one can avoid head injury entirely.

Perhaps most worryingly of all, even the best of the best rugby players in New Zealand are aware of the risks they are taking. Kieran Read has said that he intends to encourage his children into cricket on the grounds that rugby is too dangerous, and Richie McCaw said, post-retirement, that “I don’t miss getting smashed.”

The question is this: what risk of permanent brain injury is considered too much, given the positive physical and social benefits that come from the game? Because if that limit is exceeded, it may be that the responsible thing to do, from the Government’s perspective, is to ban it. After all, New Zealand schools banned Bull Rush with very little sentiment because of head injury concerns, so why couldn’t they do the same for rugby?

Recent studies on NFL players suggest that the incidence rate of brain damage in adult professional collision sports is many times higher than was previously suspected. It seems that, as brain scanning technology continues to improve, we are gathering a more refined appreciation of how vulnerable the brain really is to repeated blunt force trauma.

Rugby is different to American football, of course, because in rugby the tackle is made with the shoulder, whereas in American football tackles are often made with the head in a manner akin to a charging rhinoceros. But that’s merely a difference in degree, not in category. Rugby is still a sport based around putting the ball carrier on the ground through physical force, and this means the risk of head injury can only be minimised, never eliminated.

Already we’ve been able to observe a change in the culture of the sport in recent years. Avoiding head injuries is sometimes prioritised to an absurd degree, highlighted by the incident in the recent Lions tour when a Lions player leapt into the air to catch a loopy pass from halfback Conor Murray, was tackled before he hit the ground, and then was awarded a crucial penalty for having been taken out in the air.

This looks set to get even more extreme. It won’t be long until a professional match has to be stopped part way through because (for example) two tighthead props on one team have both failed head injury assessments.

This column has previously pointed out that the Government never gives rights back to the peasantry; they always take one new right away for every one they give back. Recent discussions about whether to change the cycle helmet laws have been centred around the idea that forcing people to wear a helmet discourages them from cycling. One can be certain that if we get our rights to cycle without a helmet back, pressure will begin to build to have them taken away somewhere else.

We would never argue for the game of rugby union to be banned, at any level. We don’t even support the softening of the game with the repeated TMO checks for suspected head-high tackles. But there are some wowsers and control freaks out there, and we can confidently state that they would happily ban rugby if they thought of the children long enough. It pays to stay one step ahead of them.

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If you enjoyed reading this essay, you can get a compilation of the Best VJMP Essays and Articles of 2017 from Amazon for Kindle or Amazon for CreateSpace (for international readers), or TradeMe (for Kiwis).

How Do We Know They’re Not Lying Again?

They lied last time, and they’re not sorry about it – so how do we know it’s different this time?

In 2003, Britain teamed up with America to attack Saddam Hussein’s Iraq on false pretenses, an action that would eventually lead to over 1,000,000 preventable deaths – a war crime by any standard. 15 years later, Britain is again beating the war drums over a supposed Russian assassination of a former Russian intelligence agent on British soil. The question the rest of us have to ask is obvious: how do we know they’re not lying again?

The British Prime Minister in 2003, Tony Blair, solemnly presented to the world a “dossier of death” that supposedly detailed Hussein’s arsenal of chemical and biological weapons, ready to attack Britain within 45 minutes of the Iraqi strongman giving the orders. Even worse, the dossier claimed, Hussein had procured significant amounts of uranium from African sources, enough to build 200 nuclear bombs.

We were told all this, and then told that the international community “had no choice but to act”. It was a casus belli of such strength that it was apparent there would be no talking the Anglo-Americans out of their impending action. Iraq was, in Blair’s words, “a current and serious threat to the UK national interest”.

The trouble is, all of those claims were lies.

Hussein’s Government disintegrated at the first sight of the iron wave coming their way, and the victorious Anglo-American forces scoured every square metre of the country for the chemical and biological weapons that would have been triumphantly paraded before the world’s media. Had they been found. There were no chemical and biological weapons in Iraq.

Usually when someone lies to you, and you find out about it, you don’t trust them again until you are satisfied that they have learned the value in honesty. But no contrition has been shown, ever, by any of the leaders who worked to bring about the slaughter in Iraq. Neither George W Bush nor Tony Blair have ever shown genuine regret for the invasion, or even the barest awareness that the invasion was the wrong thing to do.

Both George W Bush and Tony Blair are free men, not wanted by any Western war crimes tribunal. No Western leader openly calls for their arrest or imprisonment, despite that they murdered as many people as Pol Pot. No-one in British politics appears to be willing to commit Blair to trial for war crimes, the minimum acknowledgement necessary that the lost Iraqi lives had some value.

So why should we trust the claims of the British Government this week that the Russian state killed someone on British soil? Nothing appears to have changed since the last time they lied.

Most worryingly for New Zealand, our current Prime Minister Jacinda Ardern volunteered to work for the unapologetic war criminal for two and a half years, and after the scale of the destruction wrought in Iraq was widely known, and even after the fact that the invasion was launched on false pretenses was known. This suggests that not even our Prime Minister has the moral fibre to understand that killing a million people with lies is a bad thing and that people who do it should not be supported.

The prospect for world peace is looking grimmer, but, as this newspaper has previously written about, there’s no need to worry until the television starts telling us that Russians are mistreating babies somewhere. Then it’s time to hit the bunkers.

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If you enjoyed reading this essay, you can get a compilation of the Best VJMP Essays and Articles of 2017 from Amazon for Kindle or Amazon for CreateSpace (for international readers), or TradeMe (for Kiwis).

A Technoshamanic Update to the Perennial Philosophy

The perennial philosophy comes and goes, all throughout time and space, being a reflection of the mind of God in the Great Fractal. In every new age it updates itself, taking a form that makes sense to the people of the time, depending on the characteristics of that age. Because technological change has been so rapid over the last 150 years, the perennial philosophy has not been able to keep up. This essay makes an attempt to do so.

The metaphors of the former age were the crucifix, the fish and the crescent, just as they were the pyramid, the bull and the sacrificial brazier in the age before that. The age that we are now entering has its own zeitgeist – perhaps it is time for a technoshamanic update to the perennial philosophy?

The perennial philosophy is informational gold and is more fundamental than language and therefore cannot be described in words. However, we can predict what some of its teachings are going to be, by applying the axiom of “As below, so above” to the modern day.

In its earlier incarnations, through the writings of Hermes Trismegistus and others, the perennial philosophy explained the metaphysical world by analogy to the natural world. “That which is above is from that which is below, and that which is below is from that which is above, working the miracles of one,” reads the Emerald Tablet, “Its father is the Sun and its mother the Moon.”

This remained an extremely effective metaphor, until today. The world of today is so bizarre, so surreal and impossible that distinguishing it from a dreamscape is no longer easy. Moreover, modern people are almost completely out of touch with the natural world – many of us haven’t so much as looked at the Moon in years.

We need a new metaphor for a new age, and virtual reality seems like the obvious replacement.

Following this line of reasoning, one might expect that the creation myths of the new century will be based around the same binary division as always but with a modern twist; in other words not of yang and yin, fire and water or Sun and Moon but of 1 and 0. The hardware is the brain, the software is the mind, and electricity is the Holy Ghost.

Different lives could be seen as nothing more than differing sets of sensory impressions upon consciousness. As long as these impressions could be accurately recorded and reproduced, there’s no reason why they couldn’t be accessible for any conscious person to experience at any time.

My own The Verity Key twisted the ordinary perception of consciousness through a machine that could replace the consciousness of another person with that of the operator of the eponymous device. The idea was to play on the usual belief of the reader that their consciousness was directly connected to their physical body, and could never be separated.

This played with the idea of the Great Fractal, which is conceptualised as an immense algorithm that calculates all of the possible combinations of senses that make up the illusion of the material world. This is a modern way of expressing how all things flow from one, i.e. “all created objects come from one thing, an undifferentiated primal matter”.

In other words, all of the contents of consciousness ultimately flow from consciousness itself, because nothing more than consciousness is needed to create them all – a fact known to all who have managed to purify their consciousness to the level of gold and thereby completed the Philosopher’s Stone.

Other ancient alchemical or hermetic beliefs can likewise be transliterated into a modern context.

The laws of karma can be expressed in terms of frequency, which no-one understood before the days of widespread radio, and which now everyone does. If one can imagine such a thing as a frequency of consciousness, a higher frequency would produce a more harmonious tone and joy among those who heard it, whereas a lower frequency would produce a discordant tone and fear among those who heard it.

A technoshaman might contend that, upon the expiration of one’s physical body, the frequency of consciousness that one had cultivated is the only thing that passes into the next world. They might even go as far as to contend that this frequency will attract those of a like frequency, and therefore that, post-death, one’s frequency dictates which part of the Great Fractal one’s consciousness becomes attuned to and the frequency of those who populate it (until, of course, one dies there as well).

One’s “frequency of consciousness” can here be likened to an analog television or radio signal. The more pleasurable frequencies are not necessarily the first ones discovered, or the most popular ones, and they certainly aren’t the easiest to tune into. In order to tune into higher frequencies one must know where to find them on the dial.

The alchemical quest of transforming lead into gold is a physicalist metaphor for the mystical quest that, in modern language, could be said to be about tuning a low frequency of consciousness into a higher one.

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If you enjoyed reading this essay, you can get a compilation of the Best VJMP Essays and Articles of 2017 from Amazon for Kindle or Amazon for CreateSpace (for international readers), or TradeMe (for Kiwis).